Congrats on the Anova. If you are like me, you are going to love it, and want to use it for all sorts of other things (it is great for reheating frozen stuff, by the way). As for your meat question, I'm not sure whether it would turn it into pulled beef, as someone else posted above, but I would say to set it at whatever temperature you like your meat at (135? 140?), and adjust from there. As has been mentioned, you can always increase the time of the reverse sear if it is more underdone than you like. I suspect the pulled beef situation is more a function of time than temperature.